John J Wasenko

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Five distinct stages have been defined for the magnetic resonance (MR) appearance of intraparenchymal hematomas in the brain: hyperacute, acute, early subacute, late subacute and chronic. Despite the extensive study of the evolution of hematomas there has been little attention given to the MR appearance of the posthemorrhagic state within the initial hours(More)
OBJECTIVE Cerebral venous thrombosis is often associated with nonspecific clinical complaints. In addition, the imaging findings are often subtle. Underdiagnosis or misdiagnosis of cerebral venous thrombosis can lead to severe consequences, including hemorrhagic infarction and death. CONCLUSION This article reviews the radiologic findings and diagnostic(More)
Four patients with Sturge-Weber syndrome were evaluated with CT and MR. MR demonstrated the characteristic features of the disease: cerebral atrophy (four patients), ipsilateral bone and sinus hypertrophy (three), ocular findings (one), intracranial calcification (four), prominent deep venous system (three), and enlarged choroid plexus (two). CT(More)
We report five cases of tumors occurring in three children and in two adults. The tumors had unusual histomorphology and a mixture of ependymal and piloid-like astrocytic features and a myxoid stroma similar to myxopapillary ependymomas. MR imaging in three of the cases showed aggressive, intensely enhancing partially cystic hypothalamic-suprasellar masses(More)
Mesenrhombencephalitis is a rare inflammatory process involving the midbrain, pons, and medulla. The diagnosis is difficult as clinical and laboratory findings may be nonspecific. Magnetic resonance (MR) imaging demonstrates abnormal T2 signal in the brainstem, which can suggest the diagnosis. The clinical, laboratory and MR imaging findings are described(More)
PURPOSE To describe the MR appearance of cystic meningiomas, and to correlate the MR appearance with the surgical and neuropathologic findings. METHODS Eight patients with cysts associated with meningiomas were studied on a 1.5-T MR system. Unenhanced sagittal T1- and axial T2-weighted images were obtained in all patients. Axial and coronal gadopentetate(More)
A homogeneously enhancing cervical cord lesion and multiple ring-enhancing brain lesions were detected with MR imaging in a 41-year-old woman with a staphylococcal septicemia. The brain and spinal cord lesions diminished in size after antibiotic therapy. Although no biopsy was performed, we believe, on the basis of the clinical outcome, that the spinal cord(More)
Rapid sequential computed tomography of the brain after the bolus injection of contrast material provides invaluable information as to the characteristic blood flow of intracranial lesions in a noninvasive manner. Plotted dynamic curves permit accurate diagnosis of particularly difficult cases of infarcts and neoplasms. Dynamic computed tomographic (CT)(More)
Gossypol, a polyphenolic compound which depletes cellular energy by inhibition of several intracellular dehydrogenases, has been shown to have antiproliferative activity against human glial tumor cell lines in vitro and in nude mouse xenografts. Human trials of gossypol as a male contraceptive have demonstrated safety of long-term administration. We studied(More)
CT easily diagnoses epidural hematomas. The appearance of an epidural hematoma may be delayed by compression from a contralateral lesion. The possibility of a delayed epidural hematoma should be kept in mind in the presence of additional findings such as a skull fracture contralateral to the original lesion or decompression of the epidural hematoma into(More)