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BACKGROUND S. cerevisiae cells must grow to a critical size in G1 in order to pass start and enter the cell cycle. A recent study proposed that in addition to the mother size control in G1, the bud must grow to a critical bud size in G2 in order to enter mitosis. Insufficient bud size would cause G2 arrest enforced by the mitotic inhibitor Swe1p, explaining(More)
The objective of this study was to assess potential functional attenuation or inactivation of the intra-S checkpoint during melanoma development. Proliferating cultures of skin melanocytes, fibroblasts, and melanoma cell lines were exposed to increasing fluences of UVC and intra-S checkpoint responses were quantified. Melanocytes displayed stereotypic(More)
The Institute of Medicine's 2000 report drew attention to both U.S. health care agencies and the medication errors that occur within them. However, this attention focused on a more basic and fundamental issue within the medication error concern: nurses' mathematical skills and competence. This article describes a nationwide study assessing processes to(More)
New and recent graduates of schools of nursing have limited mathematical skills for medication administration. The purpose of this article is to provide a prescription for change to address the issue of limited math skills for medication administration. The authors recommend three areas of needed change: relationships, practice, and expectations. These(More)
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