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PACAP type I receptor activation regulates ECL cells and gastric acid secretion.

• Ningfeng Zeng, Christoph Athmann, +5 authors Joseph R Pisegna
• The Journal of clinical investigation
• 1999

Pituitary adenylate cyclase activating polypeptide (PACAP) is present in gastric nerves, and PACAP receptors (PAC1) are found on gastric enterochromaffin-like (ECL) cells. Expression of PAC1 splice… (More)

Gastric acid secretion rate and buffer content of the stomach after eating. Results in normal subjects and in patients with duodenal ulcer.

• John S. Fordtran, John H. Walsh
• The Journal of clinical investigation
• 1973

New methods are described by which the buffer content and the rate and pattern of net gastric acid secretion in human subjects fed normal meals can be measured by use of sodium bicarbonate infusion… (More)

Gastrin, CCK, signaling, and cancer.

• Enrique 4 Rozengurt, John H. Walsh
• Annual review of physiology
• 2001

Gastrin, produced by G cells in the gastric antrum, has been identified as the circulating hormone responsible for stimulation of acid secretion from the parietal cell. Gastrin also acts as a potent… (More)

Primary structures of PYY, [Pro(34)]PYY, and PYY-(3-36) confer different conformations and receptor selectivity.

• David A. Keire, Peter J. Mannon, Masayuki Kobayashi, John H. Walsh, Travis E. Solomon, Joseph R. Reeve
• American journal of physiology. Gastrointestinal…
• 2000

We synthesized PYY-(1-36) (nonselective between Y(1) and Y(2) receptor subtype agonists), [Pro(34)]PYY (selective for Y(1)), and PYY-(3-36) (selective for Y(2)) to determine whether solution… (More)

The treatment of Helicobacter pylori infection in the management of peptic ulcer disease.

• John H. Walsh, Walter L. Peterson
• The New England journal of medicine
• 1995

Antimicrobial therapy against H. pylori is indicated for all patients with documented peptic ulcer disease who have evidence of the infection. The regimen of first choice, selected on the basis of… (More)

Gastric and cephalic stimulation of human pancreatic polypeptide release.

• Ian Lance Taylor, Mark Feldman, Charles T. Richardson, John H. Walsh
• Gastroenterology
• 1978

Cholecystokinin inhibits gastric acid secretion through type "A" cholecystokinin receptors and somatostatin in rats.

• K C Kent Lloyd, HelenE. Raybould, John H. Walsh
• The American journal of physiology
• 1992

The purpose of this study was to determine whether selective antagonism of type "A" cholecystokinin (CCK) receptors blocks inhibition of gastric acid secretion produced by CCK and whether this… (More)

Role of gastrin heptadecapeptide in the acid secretory response to amino acids in man.

• Mark Feldman, John H. Walsh, Helen C. Wong, Charles T. Richardson
• The Journal of clinical investigation
• 1978

Amino acids and peptides release gastrin and stimulate gastric acid secretion. However, the relation between gastrin release and acid secretory response is unclear. An isotonic mixed amino acid… (More)

Studies on the role of cephalic-vagal stimulation in the acid secretory response to eating in normal human subjects.

• Charles T. Richardson, John H. Walsh, Karen A. Cooper, Mark Feldman, John S. Fordtran
• The Journal of clinical investigation
• 1977

These experiments were performed to determine the importance of cephalic-vagal stimulation in the acid secretory response to eating in normal human subjects. Cephalic stimulation was induced by a… (More)

Clearance and acid-stimulating action of human big and little gastrins in duodenal ulcer subjects.

• John H. Walsh, Jon I. Isenberg, J Ansfield, Vernon Maxwell
• The Journal of clinical investigation
• 1976

Acid-stimulating action and clearance of pure natural human big gastriin (HG-34-I) and little gastrin (HG-17-I) were assessed in four male subjects with inactive duodenal ulcer (DU) disease.… (More)

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