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In this paper, we discuss the need for accurate skills assessments of employees in large, global, client-facing enterprises and shortcomings of existing systems for obtaining and managing expertise. We describe enterprise and social data that can be mined to improve skill assessment processes. We propose a matrix completion approach with side information(More)
Assessing and managing the expertise of employees in knowledge and service industries is critical because human capital is the key differentiator among companies. Moreover, professional social networks are becoming increasingly popular. Besides the well-known public professional social network site Linked In, enterprise social networks are also now being(More)
In the rapidly changing technological world of today, new technical areas emerge quickly, and new skills related to them garner high demand. In this paper, our goal is to recommend experts for new skills and skill topics. We propose multiple predictive models to utilize data from different enterprise sources: employee assessment data, free-text skill(More)
Since their introduction in 1977 [1], the angiotensin converting enzyme (ACE) inhibitors have rapidly gained acceptance as suitable initial drug therapy for the treatment of high blood pressure [2]. Furthermore, they are becoming important members of a therapeutic armamentarium designed not only to lower blood pressure, but also to prevent and/or attenuate(More)
Calcium antagonists (C-A) induce different, renal hemodynamic alterations. They reduce afferent arteriolar resistance and do not change glomerular filtration rate. C-A prevent acute renal failure, especially after kidney transplantation. Calcium antagonists decrease nephrotoxicity of cyclosporine and radiocontrast media. C-A are recommended in the therapy(More)
The natural course of essential hypertensive renal disease is characterized by a slowly progressive impairment of renal function. Initially, the changes are functional and reversible; however, structural changes gradually occur, leading to hypertensive nephrosclerosis. Similarities exist between the early functional hemodynamic changes observed in the(More)
This review focuses on the effects of calcium antagonists on renal function in hypertensive human subjects. Specifically assessed are the acute and chronic effects of diltiazem, verapamil, amlodipine, felodipine, isradipine, nicardipine, nifedipine, and nitrendipine on glomerular filtration rate; effective renal plasma flow/renal blood flow; renal vascular(More)
The peer review system used by our j ournal maintains academic standards yet ultimately depends on the energy and skills of anonymous referees. Referees are expected to give such help completely on a voluntary basis, often without adequate recognition. This journal has now instituted a scheme to acknowledge outstanding referees, who will be selected in part(More)
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