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The cardiovascular response to changes in posture has been the focus of numerous investigations in the past. Yet despite considerable, targeted experimental effort, the mechanisms underlying orthostatic intolerance (OI) following spaceflight remain elusive. The number of hypotheses still under consideration and the lack of a single unifying theory of the(More)
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a progressive neurological disorder that affects older adult carriers, predominantly males, of premutation alleles (55 to 200 CGG repeats) of the fragile X (FMR1) gene. Principal features of FXTAS are intention tremor, ataxia, parkinsonism, cognitive decline, and peripheral neuropathy; ancillary(More)
BACKGROUND Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but do not adequately address the process of identifying and filling gaps in the reaction network, and verifying that the network is suitable for systems level analysis. Thus, current(More)
We develop a framework for analyzing an executives own-company stockholding and work effort preferences. The executive, characterized by risk aversion and work effectiveness parameters , invests his personal wealth without constraint in the financial market, including the stock of his own company whose value he can directly influence with work effort. The(More)
  • Gunther Hellman, Randall L Schweller, Jeffrey W Taliaferro, William C Wohlforth, Jeffrey W Legro, Andrew Moravcsik +17 others
  • 2003
In " Is Anybody Still a Realist? " Jeffrey Legro and Andrew Moravcsik craft a curiously rigid doctrine for realism and then puzzle over why the eld is crowded with apos-tates. 1 The answer, I propose, is that the church of realism can be a bit more catholic than Legro and Moravcsik claim. Legro and Moravcsik have written out of the book of realism a crucial(More)
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