John F . Payne

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PURPOSE To assess prospectively a treat-and-extend (TREX) management strategy compared with monthly dosing of intravitreal ranibizumab in treatment-naïve neovascular age-related macular degeneration (AMD) patients. DESIGN Phase IIIb, multicenter, randomized, controlled clinical trial. PARTICIPANTS Sixty patients with treatment-naïve neovascular AMD(More)
OBJECTIVE To describe the clinical features and imaging characteristics in unilateral acute idiopathic maculopathy. METHODS Retrospective review of 4 patients with a diagnosis of unilateral acute idiopathic maculopathy. Clinical characteristics (age, symptoms, Snellen visual acuity, and funduscopic features) and images from spectral-domain optical(More)
PURPOSE Assessment of visual outcome of pediatric eyes that underwent cataract extraction with primary intraocular lens (IOL) implantation at a single center. METHODS A retrospective review of charts of 510 consecutive pediatric patients that underwent cataract extraction was performed. Exclusion criteria were traumatic cataract, secondary IOL(More)
OBJECTIVE To assess the relationship between vitamin D status and diabetic retinopathy. METHODS A clinic-based, cross-sectional study was conducted at Emory University, Atlanta, Georgia. Overall, 221 patients were classified into 5 groups based on diabetes status and retinopathy findings: no diabetes or ocular disease (n = 47), no diabetes with ocular(More)
PURPOSE To assess the variation in macular thickness measurements in healthy Caucasian and African American men and women through Stratus OCT optical coherence tomography (OCT-3). METHODS One hundred sixty-six eyes of 83 healthy patients underwent complete ophthalmologic examination in this prospective study. Exclusion criteria included a diagnosis of(More)
PURPOSE To assess the relationship between serum insulin-like growth factor I (IGF-I) and diabetic retinopathy. METHODS This was a clinic-based cross-sectional study conducted at the Emory Eye Center. A total of 225 subjects were classified into four groups, based on diabetes status and retinopathy findings: no diabetes mellitus (no DM; n=99), diabetes(More)
PURPOSE To report the outcomes after cataract extraction in eyes previously treated for retinoblastoma. METHODS We reviewed the medical records of consecutive patients treated with cataract extraction at our institution for radiation-induced cataract following retinoblastoma treatment between 1992 and 2007. RESULTS Twelve eyes of 11 patients were(More)
An 82-year-old man with hypothyroidism had vertical diplopia and swelling around his left eye. Visual acuity was 20/20 OD and 20/50 OS. There was moderate blepharoptosis and edema of the left eyelids and superior scleral show of the right eye. The left eye showed 4 mm of proptosis, motility restriction, afferent pupillary defect, and normal optic disc.(More)
PURPOSE To determine the utility of logarithmic transformation of spectral-domain optical coherence tomography (logSD-OCT) retinal thickness data for assessment of clinically meaningful changes in uveitis-associated macular edema. METHODS Patients with noninfectious uveitis-associated macular edema at our institution between August 2010 and March 2011(More)
metronidazole, 1 g twice daily, his neurologic condition improved from being unable to walk (0/5 strength) to 4/5 lower-extremity strength. He was discharged for rehabilitation. Intravenous treatment with ceftriaxone was continued for 12 weeks. On follow-up examination 7 months after his initial visit to the ophthalmology clinic, best-corrected visual(More)