John Donovan

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Follicular lymphomas (FLs) are neoplastic counterparts of normal germinal center (GC) B cells. FLs are characterized by t(14;18) with deregulation of the Bcl-2 (BCL2) gene. The presence of t(14;18) and overexpression of Bcl-2 is necessary, but not sufficient, to cause this disease. An array containing 588 complementary DNAs (cDNAs) was used to compare the(More)
Description: The authoritative reference on HCS in biological and pharmaceutical research High Content Screening (HCS) has been a leading methodology in toxicology studies for years. Recent advances have broadened the range of applications to encompass new areas. High Content Screening: Science, Techniques, and Applications provides comprehensive coverage(More)
Recently, we read the observation by Walker et al. [1] published in the Journal of Medical Toxicology and commend the authors for their recognition of anticholinergic syndrome. However, we are distressed that a 13-year-old pediatric patient was treated with a novel drug without first having received the known antidote for anticholinergic delirium,(More)
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