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Palliation of hypoplastic left-heart syndrome involves use of the morphologic right ventricle as the systemic ventricle and the tricuspid valve (in cases of mitral atresia/stenosis) or the common atrioventricular valve (in cases of malaligned atrioventricular canal) as the systemic atrioventricular valve. To determine the relationship between tricuspid or(More)
Virtually all forms of congenital heart disease can be repaired or significantly palliated. The risk of surgery in infancy continues to decline, and many lesions are being routinely repaired at an early age. This may permit an improved functional result later in life. Other recent advances include the arterial switch procedure for transposition of the great(More)
From August, 1985, through August, 1987, 104 consecutive, nonselected neonates underwent palliation of hypoplastic left heart syndrome. The technique included pulmonary artery homograft augmentation of the diminutive ascending aorta and aortic arch, atrial septectomy, transection of the main pulmonary artery with patch closure of the distal main pulmonary(More)
Clinical studies have suggested that quinidine is less effective when used for the treatment of atrial arrhythmias in pediatric patients compared with its clinical effectiveness in the adult patient population. Age-related changes in the cardiac actions of quinidine on action potential duration and interaction with potassium channels in several mammalian(More)
Sixty-five consecutive patients with hypoplastic left heart syndrome underwent preoperative two-dimensional echocardiographic examination (and Doppler examinations in 33) to assess parameters potentially predictive of early (less than or equal to 30 days) mortality after palliative surgery. The six anatomic and physiologic factors considered were right(More)
To determine whether preoperative demographic and metabolic variables correlated with early or late survival following palliative surgery for hypoplastic left heart syndrome, we reviewed the charts of 89 patients operated upon from October 1984 to January 1987. The variables analyzed were age at operation, lowest preoperative pH and H2CO3, highest(More)
The importance of pulmonary artery size and the value of a standardized pulmonary artery index (PAI) in predicting outcome after Fontan's repair have previously been reported and questioned. We retrospectively reviewed 29 patients undergoing modified Fontan repair at The Children's Hospital of Philadelphia to examine the relation between preoperative PAI(More)
Late survival and freedom from myocardial infarction were determined for 192 patients with coronary artery disease and depressed left ventricular ejection fraction at rest (less than or equal to 35%) determined by biplane angiography who were evaluated between 1970 and 1977. Seventy-seven patients had coronary artery bypass grafting and 115 patients were(More)