John Castellucci

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BACKGROUND The lack of a suitable noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our animal study was to test a new real-time three-dimensional (3D) echo imaging system for evaluating RV stroke volumes. METHODS AND RESULTS Three to 6 months before(More)
Piezoelectric micromachined ultrasound transducers (pMUTs) are a new approach for the construction of 2-D arrays for forward-looking 3-D intravascular (IVUS) and intracardiac (ICE) imaging. Two-dimensional pMUT test arrays containing 25 elements (5 x 5 arrays) were bulk micromachined in silicon substrates. The devices consisted of lead zirconate titanate(More)
Piezoelectric micromachined ultrasound transducer (PMUT) matrix arrays were fabricated containing novel through-silicon interconnects and integrated into intracardiac catheters for in vivo real-time 3-D imaging. PMUT arrays with rectangular apertures containing 256 and 512 active elements were fabricated and operated at 5 MHz. The arrays were bulk(More)
BACKGROUND The accuracy of conventional 2-dimensional echocardiographic and Doppler techniques for the quantification of valvular regurgitation remains controversial. In this study, we examined the ability of real-time 3-dimensional (RT3D) echocardiography to quantify aortic regurgitation by computing aortic regurgitant volume as the difference between 3D(More)
Real-time, three-dimensional (RT3D) ultrasound allows video frame rate volumetric imaging. The ability to acquire full three-dimensional (3-D) image data in real-time is particularly helpful for applications such as cardiac imaging, which require visualization of complex and dynamic 3-D anatomy. Volume rendering provides a method for intuitive graphical(More)
RATIONALE AND OBJECTIVES Real-time tomographic reflection (RTTR) permits in situ visualization of tomographic images so that natural hand-eye coordination can be used directly during invasive procedures. The method uses a half-silvered mirror to merge the visual outer surface of the patient with a simultaneous scan of the patient's interior without(More)
The Live Volumetric Imaging (LVI) catheter is capable of real-time 3D intracardiac echo (ICE) imaging, uniquely providing full volume sectors with deep penetration depth and high volume frame rate. The key enabling technology in this catheter is an integrated piezoelectric micromachined ultrasound transducer (pMUT), a novel matrix phased array transducer(More)
We describe an advanced real-time high-speed echocardiographic system with live display while scanning. Images are acquired at rates up to 1000 per second for adult cardiac applications and are stored in computer memory. Images may be played back in slow motion or frame by frame to analyze cardiac motion at the millisecond time scale. Images are acquired(More)
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