John C. Blackburn

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High resolution 1H NMR spectroscopy has been employed to investigate the detection and quantification of the illicit "date-rape" drug gamma-hydroxybutyrate (GHB) in both human saliva and a commonly-consumed low-alcohol beer product. Data acquired revealed that this multicomponent analytical technique provided unequivocal evidence for the detection of this(More)
Deuterium quadrupole NMR line shapes were simulated to match experimental spectra of liquid crystalline phases observed in the cesium and sodium n-tetradecanoate-Dz0 systems. The line shapes of single-phase samples with both uniaxial and biaxial symmetry were accurately simulated. Line shape simulations were matched to experimental spectra by minimizing the(More)
1. ABSTRACT The Airborne Aero-Optics Laboratory (AAOL) was designed to measure the effects of turbulent flow on the wavefront of a laser projected from an airplane in flight. An integrated line-of-sight model that predicts closed-loop jitter of the AAOL system is presented. The influence of model uncertainty with model tuning based on available experimental(More)
A system is described for determination of discrete pulse train characteristics of multi spot laser delivery systems for retinal photocoagulation. While photodiodes provide an ideal detection mechanism, measurement artifacts can potentially be introduced by the spatial pattern of the delivered beam relative to a discrete photodiode element. This problem was(More)
Oral rinse formulations containing chlorite anion (ClO2 −) as an active agent exert a range of valuable oral healthcare activities. However, salivary biomolecules which chemically react with this oxidant can, at least in principle, serve as potentially significant barriers to these therapeutic properties in the oral environment. Therefore, in this(More)
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