John C. Arnold

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BACKGROUND We sought to compare the effects on ophthalmic function of coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) and off-pump (OPCAB) grafting and to investigate whether retinal microvascular damage is associated with markers of cerebral injury. METHODS AND RESULTS Retinal microvascular damage was assessed by fluorescein(More)
Influenza-specific hemaggluitination inhibition (HAI) antibody titer, an indicator of immunity to influenza, is often used to measure exposure to influenza in surveillance and immunogenicity studies. Traditionally, serum has been the specimen of choice for HAI assays, but a desire to reduce the amount of blood collected during studies and the availability(More)
BACKGROUND One of the most important decisions in the treatment of osteoarticular infections is the time at which parenteral therapy can be changed to oral therapy. C-reactive protein (CRP) is an acute inflammatory indicator with a half-life of 19 hours and thus can be helpful in assessing the adequacy of therapy for bacterial infections. At our(More)
to the following: (a) the Guidance may be used solely for your personal, informational, non-commercial use; (b) the Guidance may not be modified or altered in any way; (c) the Guidance may not be redistributed; and (d) the trademark, copyright or other notices may not be removed. You may quote portions of the Guidance as permitted by the Fair Use provisions(More)
A 7-year-old boy with a history of recurrent acute lymphoblastic leukemia (ALL), in remission, presented to primary care clinic after 2 days of progressive right hip pain with weight-bearing activities. He was otherwise asymptomatic at the time of presentation. Blood cultures revealed Gram-negative diplococci, which prompted an MRI that was significant for(More)
With so many developments and opportunities in play, SEWPC's remit and membership is changing. The Committee will keep its formal Terms of Reference and Scheme of Membership documents under review and will come back with a formal proposal to Academic Board. 4 STUDENT ENGAGEMENT STRATEGY Noted 4.1 Both financially and in terms of staff numbers significant(More)
BACKGROUND Adenovirus is a recognized cause of influenza-like illness (ILI). The proportion of ILI attributable to adenovirus is not known. Moreover, knowledge gaps remain with respect to the epidemiologic, virologic, and clinical characteristics of adenovirus-associated ILI among otherwise healthy individuals. METHODS An observational, longitudinal study(More)
BACKGROUND To develop content validity of a comprehensive patient-reported outcome (PRO) measure following current best scientific methodology to standardize assessment of influenza (flu) symptoms in clinical research. METHODS Stage I (Concept Elicitation): 1:1 telephone interviews with influenza-positive adults (≥18 years) in the US and Mexico within 7(More)
BACKGROUND AND OBJECTIVES The Military Health System provides universal coverage of all recommended childhood vaccinations. Few studies have examined the effect that being insured by the Military Health System has on childhood vaccination coverage. The purpose of this study was to compare the coverage of the universally recommended vaccines among military(More)