Learn More
Timothy H. Dellit, Robert C. Owens, John E. McGowan, Jr., Dale N. Gerding, Robert A. Weinstein, John P. Burke, W. Charles Huskins, David L. Paterson, Neil O. Fishman, Christopher F. Carpenter, P. J. Brennan, Marianne Billeter, and Thomas M. Hooton Harborview Medical Center and the University of Washington, Seattle; Maine Medical Center, Portland; Emory(More)
OBJECTIVE To determine the excess length of stay, extra costs, and mortality attributable to adverse drug events (ADEs) in hospitalized patients. DESIGN Matched case-control study. SETTING The LDS Hospital, a tertiary care health care institution. PATIENTS All patients admitted to LDS Hospital from January 1, 1990, to December 31, 1993, were eligible.(More)
The Swift-Hohenberg equation with quadratic and cubic nonlinearities exhibits a remarkable wealth of stable spatially localized states. The presence of these states is related to a phenomenon called homoclinic snaking. Numerical computations are used to illustrate the changes in the localized solution as it grows in spatial extent and to determine the(More)
BACKGROUND AND METHODS Optimal decisions about the use of antibiotics and other antiinfective agents in critically ill patients require access to a large amount of complex information. We have developed a computerized decision-support program linked to computer-based patient records that can assist physicians in the use of antiinfective agents and improve(More)
The bistable Swift-Hohenberg equation exhibits multiple stable and unstable spatially localized states of arbitrary length in the vicinity of the Maxwell point between spatially homogeneous and periodic states. These states are organized in a characteristic snakes-and-ladders structure. The origin of this structure in one spatial dimension is reviewed, and(More)
BACKGROUND Randomized, controlled trials have shown that prophylactic antibiotics are effective in preventing surgical-wound infections. However, it is uncertain how the timing of antibiotic administration affects the risk of surgical-wound infection in actual clinical practice. METHODS We prospectively monitored the timing of antibiotic prophylaxis and(More)
Objective: To develop a new method to improve the detection and characterization of adverse drug events (ADEs) in hospital patients. Design: Prospective study of all patients admitted to our hospital over an 18 month period. Setting: LDS Hospital, Salt Lake City, Utah, a 520-bed tertiary care center affiliated with the University of Utah School of Medicine,(More)
PURPOSE There is no consensus on what constitutes an adequate surgical margin in patients receiving breast-conserving surgery (BCS) and postoperative radiation therapy (RT) for ductal carcinoma in situ (DCIS). Inadequate margins may result in high local recurrence, and excessively large resections may lead to poor cosmetic outcome without oncologic benefit.(More)