John B Young

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Frailty is the most problematic expression of population ageing. It is a state of vulnerability to poor resolution of homoeostasis after a stressor event and is a consequence of cumulative decline in many physiological systems during a lifetime. This cumulative decline depletes homoeostatic reserves until minor stressor events trigger disproportionate(More)
BACKGROUND Community physiotherapy is often prescribed for stroke patients with long-term mobility problems. We aimed to assess the effectiveness of this treatment in patients who had mobility problems 1 year after stroke. METHODS We screened 359 patients older than 50 years for a single-masked, randomised controlled trial to assess the effects of(More)
BACKGROUND delirium is a common clinical problem and is associated with adverse health outcomes. Many medications have been associated with the development of delirium, but the strength of the associations is uncertain and it is unclear which medications should be avoided in people at risk of delirium. METHODS we conducted a systematic review to identify(More)
BACKGROUND frailty is a state of vulnerability to adverse outcomes. Routine identification of frailty is recommended in international guidance. This systematic review investigates the diagnostic test accuracy (DTA) of simple instruments for identifying frailty in community-dwelling older people. METHODS the review methodology followed Cochrane procedures.(More)
OBJECTIVE To assess the effectiveness of information provision strategies in improving the outcome for stroke patients and/or their identified caregivers. DATA SOURCES We searched: the Cochrane Stroke Group Trials Register; the Cochrane Central Register of Controlled Trials; electronic databases MEDLINE; EMBASE; CINAHL; PsycINFO; Science Citation Index(More)
BACKGROUND Standing is believed to have benefits in addressing motor and sensory impairments after stroke. One device to facilitate standing for severely disabled patients is the Oswestry Standing Frame. OBJECTIVE To evaluate the effectiveness of the Oswestry Standing Frame for severely disabled stroke patients. DESIGN A single centre, randomized(More)
BACKGROUND frailty is an especially problematic expression of population ageing. International guidelines recommend routine identification of frailty to provide evidence-based treatment, but currently available tools require additional resource. OBJECTIVES to develop and validate an electronic frailty index (eFI) using routinely available primary care(More)