John B Chiavetta

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In the yeast Saccharomyces cerevisiae, Cdc24p functions at least in part as a guanine-nucleotide-exchange factor for the Rho-family GTPase Cdc42p. A genetic screen designed to identify possible additional targets of Cdc24p instead identified two previously known genes, MSB1 and CLA4, and one novel gene, designated MSB3, all of which appear to function in(More)
PURPOSE This study was performed to determine whether subtle anterior subluxation occurs in anterior cruciate ligament (ACL)-deficient knees with the knee in full extension. TYPE OF STUDY Radiographic evaluation of tibial position in ACL-intact and ACL-deficient knees. METHODS Twenty-four subjects with arthroscopically documented ACL-deficient knees(More)
Graft failure in anterior cruciate ligament (ACL) reconstruction can result from anterior placement of the tibial tunnel. Conventional radiographic evaluation of this problem does not take into account potential changes in tibio-femoral relationship caused by ACL instability. A retrospective radiographic evaluation of failed as well as successful ACL(More)
BACKGROUND Patients with short stature and osseous deformities resulting from osteochondrodysplasia frequently have premature development of advanced degenerative disease of the hip and thus may require total hip arthroplasty. The outcome of total hip arthroplasty in this group of young patients is unknown. In this study, we evaluated the long-term clinical(More)
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