John Anthony Gerard Scott

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OBJECTIVES The purpose of this study was to evaluate functional impairment in a group of patients with bipolar disorder in remission and to determine the extent of relationships between overall functioning and current depressive, manic and panic spectrum symptoms. METHOD A subset of the patient population at the Pittsburgh site of the Systematic Treatment(More)
RATIONALE Impulsivity is related to greater risk of nicotine dependence, perhaps by enhancing sensitivity to nicotine's reinforcing and rewarding effects during initial smoking experiences. OBJECTIVE We examined the influence of impulsivity characteristics on acute sensitivity to nicotine reward, reinforcement, and other effects in 131 young adult(More)
  • A J Brent, I Ahmed, M Ndiritu, P Lewa, C Ngetsa, B Lowe +4 others
  • 2006
BACKGROUND Estimates of the burden of invasive bacterial disease in sub-Saharan Africa have previously relied on selected groups of patients, such as inpatients; they are, therefore, probably underestimated, potentially hampering vaccine implementation. Our aim was to assess the incidence of bacteraemia in all children presenting to a hospital in Kenya,(More)
INTRODUCTION The time of day in which craving, withdrawal, and other tobacco abstinence symptoms are assessed may moderate the influences of abstinence or medication on those symptoms. METHODS Participants were 209 smokers participating in a 4-week crossover study assessing symptoms due to smoking versus abstinence and while using nicotine (21 mg) versus(More)
OBJECTIVE To assess the effects of major multi-sport events on health and socioeconomic determinants of health in the population of the city hosting the event. DESIGN Systematic review. DATA SOURCES We searched the following sources without language restrictions for papers published between 1978 and 2008: Applied Social Science Index and Abstracts(More)
Initial sensitivity to nicotine's effects during early exposure to tobacco may relate to dependence vulnerability. We examined the association of initial nicotine sensitivity with individual difference factors of sex, other drug use history (i.e. cross-tolerance or cross-sensitization), and parental smoking status in young adult nonsmokers (N=131).(More)
BACKGROUND E-health has become a burgeoning field in which health professionals and health consumers create and seek information. E-health refers to internet-based health care and information delivery and seeks to improve health service locally, regionally and worldwide. E-sexual health presents new opportunities to provide online sexual health services(More)
Memory B cells are long-lived and could contribute to persistence of humoral immunity by maintaining the plasma-cell pool or making recall responses upon re-exposure to an antigen. We determined the ability of a pneumococcal conjugate vaccine to induce anti-pneumococcal memory B cells. Frequencies of memory B cells against pneumococcal capsular(More)
BACKGROUND Despite the publication of several studies on the subject, there is significant uncertainty regarding the burden of disease among adults in sub-Saharan Africa (sSA). OBJECTIVES To describe the breadth of available data regarding causes of admission to hospital, to systematically analyze the methodological quality of these studies, and to(More)
BACKGROUND To better understand the longitudinal trend in the proportion of techniques employed for cerebral aneurysm treatment, we reviewed our experience with 2253 patients over the last 11 years. METHODS We reviewed data in our prospective aneurysm database for all consecutive patients treated from January 1998 through December 2009. Data regarding(More)