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- Shin’ichi Akiyama, Anthony T. Fojo, John A Hanover, Ira Pastan, Malcolm Gottesman
- Somatic cell and molecular genetics
- 1985
Human KB cell lines resistant to high levels of colchicine were isolated by several successive single-step selections. Most of these selection steps resulted in cross-resistance to vincristine,… (More)
- William A. Lubas, D. W. Frank, M. Krause, John A Hanover
- The Journal of biological chemistry
- 1997
O-Linked GlcNAc addition and phosphorylation may compete for sites on nuclear pore proteins and transcription factors. We sequenced O-linked GlcNAc transferase from rabbit blood and identified the… (More)
- James M Holaska, Ben E. Black, Dona C. Love, John A Hanover, John D. Leszyk, Bryce M. Paschal
- The Journal of cell biology
- 2001
In previous work, we used a permeabilized cell assay that reconstitutes nuclear export of protein kinase inhibitor (PKI) to show that cytosol contains an export activity that is distinct from Crm1… (More)
- Dona C. Love, John A Hanover
- Science's STKE : signal transduction knowledge…
- 2005
A dynamic cycle of addition and removal of O-linked N-acetylglucosamine (O-GlcNAc) at serine and threonine residues is emerging as a key regulator of nuclear and cytoplasmic protein activity. Like… (More)
- Dona C. Love, Jarema P. Kochan, Rebecca Cathey, Sang-Hoon Shin, John A Hanover
- Journal of cell science
- 2003
O-linked GlcNAc transferase (OGT) mediates a novel glycan-dependent signaling pathway, but the intracellular targeting of OGT is poorly understood. We examined the localization of OGT by… (More)
- John A Hanover, Michael W. Krause, Dona C. Love
- Biochimica et biophysica acta
- 2010
The enzymes of O-GlcNAc cycling couple the nutrient-dependent synthesis of UDP-GlcNAc to O-GlcNAc modification of Ser/Thr residues of key nuclear and cytoplasmic targets. This series of reactions… (More)
- John A Hanover
- FASEB journal : official publication of the…
- 2001
The addition of O-linked N-acetylglucosamine (O-GlcNAc) to target proteins may serve as a signaling modification analogous to protein phosphorylation. Like phosphorylation, O-GlcNAc is a dynamic… (More)
- D C Love, Tom Sweitzer, John A Hanover
- Proceedings of the National Academy of Sciences…
- 1998
The Rev protein of HIV-1 actively shuttles between nucleus and cytoplasm and mediates the export of unspliced retroviral RNAs. The localization of shuttling proteins such as Rev is controlled by the… (More)
- William A. Lubas, John A Hanover
- The Journal of biological chemistry
- 2000
O-GlcNAc transferase (OGT) modifies nuclear pore proteins and transcription factors. In Arabidopsis, the OGT homolog participates in the gibberellin signaling pathway. We and others have proposed… (More)
- John A Hanover, Michael W. Krause, Dona C. Love
- Nature Reviews Molecular Cell Biology
- 2012
O-GlcNAcylation, which is a nutrient-sensitive sugar modification, participates in the epigenetic regulation of gene expression. The enzymes involved in O-linked β-D-N-acetylglucosamine (O-GlcNAc)… (More)