Johannes Warth

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OBJECTIVES The cAMP-dependent Cl- conductance in heart is believed to be due to cardiac expression of the cystic fibrosis transmembrane conductance regulator (CFTR). While CFTR expressed in rabbit and guinea-pig heart (CFTRcardiac) is an alternatively spliced isoform of the epithelial gene product, little information is known regarding possible expression(More)
Angiotensin II (Ang II) has powerful modulatory actions on cardiovascular function that are mediated by specific receptors located on neurons within the hypothalamus and brain stem. Incubation of neuronal cocultures of rat hypothalamus and brain stem with Ang II elicits an Ang II type 1 (AT1) receptor-mediated inhibition of total outward K+ current that(More)
Article history: Received 29 October 2010 Received in revised form 28 March 2011 Accepted 6 April 2011 Available online 28 May 2011 A novel and innovative real-time Delphi technique is introduced in order to address previously identified weaknesses of the conventional Delphi method, such as complicated facilitator tasks, lack of real-time presentation of(More)
cAMP-dependent chloride channels in heart contribute to autonomic regulation of action potential duration and membrane potential and have been inferred to be due to cardiac expression of the epithelial cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. In this report, a cDNA from rabbit ventricle was isolated and sequenced, which(More)
Recent electrophysiological data suggests a number of similarities in the properties of cAMP-dependent Cl- channels in heart and cAMP-dependent Cl- channels encoded by the cystic fibrosis transmembrane conductance regulator (CFTR) gene product in various epithelial cells. We tested the hypothesis that cAMP-dependent Cl- channels in heart may be due to(More)
Conventional wisdom suggests that data quality plays a central role for compiling valid and reliable plans to make the right decisions. At the same time, it is acknowledged that planning processes are both data and knowledge intensive and characterized by the human-computer interface. However, there are limited academic investigations on how data quality(More)
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