Johannes Pohlhammer

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BACKGROUND High serum concentrations of l-arginine and l-homoarginine increase nitric oxide (NO) availability and thereby improve endothelial function. Information about the association of these markers with peripheral arterial disease (PAD) and related outcomes is sparse. METHODS l-arginine, its metabolites and l-homoarginine were analyzed in the CAVASIC(More)
The difference between literature values of ultrasonic attenuation and absorption coefficients, defined as the scatter coefficient, was related to percent wet weight collagen concentration for brain, heart, liver, kidney, and tendon, in the range of 0.7 to 7 MHz. The comparison shows that as the ultrasonic frequency increases, the scatter coefficient(More)
BACKGROUND Serum concentrations of high-sensitivity cardiac troponin T (hs-cTnT) are elevated in various diseases. The role of this marker in peripheral arterial disease (PAD) has not been fully investigated. METHODS Hs-cTnT was measured in the CAVASIC Study, a male cohort of 235 patients diagnosed with intermittent claudication and 249 age- and(More)
BACKGROUND Individuals with an impaired ventricular function have a poor prognosis due to underlying heart failure and higher mortality rates. Patients with peripheral arterial disease (PAD) represent a high-risk population for left ventricular systolic dysfunction (LVSD). METHODS The left ventricular ejection fraction (LVEF) was measured in a subset of(More)
Patients with intermittent claudication carry a high risk for cardiovascular complications. The TransAtlantic Inter-Society Consensus (TASC) Group estimated a five-year overall mortality of 30% for these patients, the majority dying from cardiovascular causes. We investigated whether this evaluation is still applicable in nowadays patients. We therefore(More)
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