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BACKGROUND This report describes a large international chocolate-associated Salmonella outbreak originating from Germany. METHODS We conducted epidemiologic investigations including a case-control study, and food safety investigations. Salmonella (S.) Oranienburg isolates were subtyped by the use of pulsed-field gel electrophoresis (PFGE). RESULTS From(More)
This paper discusses computer-supported outbreak detection using routine surveillance data, as implemented at six institutes for infectious disease control in five European countries. We give an overview of the systems used at the Statens Serum Institut (Denmark), Health Protection Agency (England, Wales and Northern Ireland), Robert Koch Institute(More)
Early detection of potential health threats is crucial for taking actions in time. It is unclear in which information source an event is reported first and, information from various sources can be complementing. Thus, it is important to search for information in a very broad range of sources. Furthermore, real-time processing is necessary to deal with the(More)
Early detection of disease outbreaks is crucial for public health officials to react and report in time. Currently, novel approaches and sources of information are investigated to address this challenge. For example, data sources such as blogs or Twitter messages become increasingly important for epidemiologic surveillance. In traditional surveillance,(More)
BACKGROUND A birth cohort dedicated to studying infections in early childhood may be assisted by parental recording of symptoms on a daily basis and a collection of biomaterials. We aimed at testing the feasibility of this approach for use in a long-term study focusing on infections in children in Germany. METHODS Parents of 1- to 3-year-old children (n =(More)
The number of asylum seekers arriving in Germany has increased rapidly since 2014 and cases of vaccine-preventable diseases at reception centres were reported. Asylum seekers 12 years and older arriving in Lower Saxony were serologically screened for antibodies against measles, rubella and varicella between November 2014 and October 2015. We calculated the(More)
Based on measles case data from pediatricians in Lower Saxony, a simulation study was conducted in order to reproduce the current vaccination-disease relationship and afrerwards predict the impact of different vaccination strategies. The programs were written in S-Plus and make use of the language's array processing facilities. The process of infection was(More)
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