Johannes Knoth

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BACKGROUND AND PURPOSE Advancements in imaging and dose delivery enable boosting of the dominant intraprostatic lesions (DIL), while maintaining organs-at-risk (OAR) tolerances. This study aimed to assess the feasibility of DIL boosting for volumetric modulated arc therapy (VMAT), intensity modulated proton therapy (IMPT) and high dose rate brachytherapy(More)
Human blood serum has been analyzed by X-ray fluorescence spectroscopy utilizing the effect of background reduction by total reflexion of the incident X-ray beam on an optical flat as sample support. For sample preparation a drop of 10 microliter serum was pipetted onto the support and dried to a thin film. The minimum detectable limit was about 1.5 mmol/l(More)
The role of multi-parametric (mp)MRI in the diagnosis and treatment of prostate cancer has increased considerably. An alternative to visual inspection of mpMRI is the evaluation using histogram-based (first order statistics) parameters and textural features (second order statistics). The aims of the present work were to investigate the relationship between(More)
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