Johanna Stolz

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Changes in [3H]-5HT and [3H]-spiperone binding in vitro and ex vivo following withdrawal from chronic administration of certain antidepressants and the 5HT antagonist metergoline were compared with changes in 5-methoxy-N′,N′-dimethyltryptamine (5MEODMT, 2.5 mg/kg) induced behaviour following acute, chronic and withdrawal from chronic treatment with the same(More)
Streptokinase, the first of the thrombolytic agents to be used in acute myocardial infarction, has now been administered to many thousands of patients with this condition. Since early intervention and accessibility of care is paramount in these patients, intravenous infusion of streptokinase has largely replaced intracoronary use. Results of major trials(More)
Acute treatment of rats with metergoline (2 mg/kg), a serotonin antagonist, prevented the behavioural syndrome produced by the serotonin agonist 5-methoxy-N',N'-dimethyltryptamine (2.5 mg/kg, 5MEODMT). dl-Propranolol (15 mg/kg) and amitriptyline (15 mg/kg) also inhibited the behavioural syndrome. The 5MEODMT behavioural syndrome was attenuated when(More)
1. Electrochemical techniques have been used to measure release of endogenous 5HT from brain regions in vitro and to record electrochemical changes induced by drugs acting on 5HT neurones in the anaesthetised and unanaesthetised rat in vivo. 2. 5HT release in vitro was observed in all regions studied. The highest level of basal release was observed in the(More)
Recent geological treatises have presented three alternative models of the origins of eukaryotes as if they merited equal treatment. However, modern biological techniques, especially nucleic acid and protein sequencing, have clearly established the validity of the symbiotic theory of the origin of eukaryotic organelles. The serial endosymbiotic theory in(More)
The effects of single and chronic doses of rolipram on the sensitivity of alpha 2-adrenoceptors have been compared with the phosphodiesterase inhibitors, isobutylmethylxanthine (IBMX) and ICI 63,197, and the antidepressant, desipramine. While pretreatment with a single dose of rolipram, ICI 63,197 or IBMX administered either 1 or 24 h prior to clonidine(More)
1. Rats were treated with acute and chronic schedules of metergoline (2.5 mg/kg I.P. twice daily) and acutely with dl-propranolol (15 mg/kg), amitriptyline (12.5 mg/kg) and fluoxetine (2 mg/kg). 2. Metergoline given both acutely and chronically blocked the behavioural response to the 5-hydroxytryptamine receptor agonist 5-methoxy-N1, N1-dimethyltryptamine(More)
  • Johanna Stolz
  • Advances in space research : the official journal…
  • 1984
The Gaia hypothesis originally proposed by James E. Lovelock states that the composition, oxidation-reduction state and temperature of the troposphere are actively regulated by the activities of the biota. The gaian concept has been extrapolated to include the composition of surface sediments through the process of biomineralization. The stratified(More)