• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • W. Tamminga, Johan Wemer, +5 authors J. H. G. Jonkman
  • Medicine
  • European Journal of Clinical Pharmacology
  • 1999 (First Publication: 7 May 1999)
  • AbstractObjective: We examined a large database containing results on CYP2D6 and CYP2C19 activity of 4301 Dutch volunteers phenotyped in the context of various clinical pharmacology studies. Continue Reading
  • W. Tamminga, Johan Wemer, Berend Oosterhuis, R. A. de Zeeuw, L. F. M. H. de Leij, J. H. G. Jonkman
  • Medicine
  • European Journal of Clinical Pharmacology
  • 2001 (First Publication: 1 December 2001)
  • Abstract. Aim: This study was performed in a sample of the Dutch population to estimate the prevalence of noncoding mutations of CYP2D6 and CYP2C19 as obtained by genotyping. In addition, theContinue Reading
  • A Le Liboux, J P Cachia, +7 authors Johan Wemer
  • Medicine
  • Journal of clinical pharmacology
  • 1999 (First Publication: 1 May 1999)
  • The pharmacokinetics and tolerability of the novel antiexcitatory agent, riluzole, were compared in 18 healthy elderly and 18 healthy gender- and weight-matched young volunteers. All participantsContinue Reading
  • A E Toet, Johan Wemer, Wim Vleeming, J D te Biesebeek, Jan Meulenbelt, Dick J de Wildt
  • Medicine
  • Human & experimental toxicology
  • 1996 (First Publication: 1 May 1996)
  • 1 Respiratory and cardiovascular failure are the princi ple toxic effects of β-blocker overdose. Respiratory arrest is the primary cause of death in β-blocker intoxicated rats. 2 The effect ofContinue Reading
  • Jaap Wieling, Wim J. Tamminga, E. P Sakiman, Berend Oosterhuis, Johan Wemer, J H Jonkman
  • Medicine
  • Therapeutic drug monitoring
  • 2000 (First Publication: 1 August 2000)
  • A bioanalytical method for the determination of dextromethorphan (DEX) and its metabolites dextrorphan (DTX), 3-methoxymorphinan (3MM), and 3-hydroxymorphinan (3HM) in human urine was developed forContinue Reading
  • Anton N M Schoffelmeer, Johan Wemer, Arie H. Mulder
  • Chemistry, Medicine
  • Neurochemistry International
  • 1981 (First Publication: 31 December 1981)
  • In this study (3)H-noradrenaline (NA) release from rat neocortex slices evoked by electrical field-stimulation (1 Hz, 12 mA, 2 msec) was compared with that induced by K(+)-depolarization (13-30 mMContinue Reading
  • Wim J. Tamminga, Johan Wemer, +6 authors Jan H. G. Jonkman
  • Medicine
  • European Journal of Clinical Pharmacology
  • 2003 (First Publication: 1 May 2003)
  • AimThe aim of the current retrospective study was to assess the influence of polymorphic drug metabolism as assessed by genotyping, on the on the utilisation of psychotropic drugs in hospitalisedContinue Reading