Johan Throne Holst

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The utility of wild-type outer membrane vesicle (wtOMV) vaccines against serogroup B (MenB) meningococcal disease has been explored since the 1970s. Public health interventions in Cuba, Norway and New Zealand have demonstrated that these protein-based vaccines can prevent MenB disease. Data from large clinical studies and retrospective statistical analyses(More)
1 PURPOSE. To examine the in vivo activation of nuclear factor (NF)-␬B in mouse lens epithelia by using bacterial lipopolysac-charide (LPS), tumor necrosis factor (TNF)-␣, and UV-B radiation. METHODS. Transgenic mice containing the NF-␬B-luciferase reporter were injected with LPS, TNF-␣ or, exposed to UV-B. After various exposure times, the mice were(More)
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