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Expansion of functionally skewed CD56-negative NK cells in chronic hepatitis C virus infection: correlation with outcome of pegylated IFN-alpha and ribavirin treatment.

• Veronica D. Gonzalez, Karolin Falconer, +5 authors Johan K Sandberg
• Journal of immunology
• 2009

NK cells are important innate immune effector cells, normally characterized as CD56(+)CD3(-) lymphocytes. In this study, we report that CD56(-)CD16(+) NK cells expand in many patients with chronic… (More)

NKG2D performs two functions in invariant NKT cells: direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d.

• Carlotta Kuylenstierna, Niklas K Björkström, +7 authors Johan K Sandberg
• European journal of immunology
• 2011

Invariant NKT cells are important in the activation and regulation of immune responses. They can also function as CD1d-restricted killer cells. However, the role of activating innate NK-cell… (More)

Exosomes from breast milk inhibit HIV-1 infection of dendritic cells and subsequent viral transfer to CD4+ T cells.

• Tanja I. Näslund, Dominic Paquin-Proulx, Patricia Torregrosa Paredes, Helen Vallhov, Johan K Sandberg, Susanne Gabrielsson
• AIDS
• 2014

OBJECTIVE To investigate whether exosomes derived from human breast milk or plasma confer protection against HIV-1 infection of monocyte-derived dendritic cells (MDDCs) and subsequent viral transfer… (More)

Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes.

• Johan K Sandberg, Noam M. Fast, Douglas F Nixon
• Journal of immunology
• 2001

CD8(+) T cells use a number of effector mechanisms to protect the host against infection. We have studied human CD8(+) T cells specific for CMV pp65(495-503) epitope, or for staphylococcal… (More)

Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection.

• Johan K Sandberg, Noam M. Fast, +8 authors Douglas F Nixon
• Journal of virology
• 2002

V alpha 24 natural killer T (NKT) cells are innate immune cells involved in regulation of immune tolerance, autoimmunity, and tumor immunity. However, the effect of human immunodeficiency virus type… (More)

Immunodominance in the CTL response against minor histocompatibility antigens: interference between responding T cells, rather than with presentation of epitopes.

• Elisabeth Z. Wolpert, Per Grufman, Johan K Sandberg, Anna Tegnesjö, Klas Kärre
• Journal of immunology
• 1998

We have investigated mechanisms involved in immunodominance of the CTL response of C57BL/6 (B6) mice against cells of BALB.B origin. This transplantation barrier consists of at least 40 minor… (More)

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection.

• Edwin Leeansyah, Anupama Ganesh, +9 authors Johan K Sandberg
• Blood
• 2013

Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved antimicrobial MR1-restricted T-cell subset. MAIT cells are CD161(+), express a V7.2 TCR, are primarily CD8(+) and numerous… (More)

Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments.

• Markus Moll, Sofia K. Andersson, Anna Smed-Sörensen, Johan K Sandberg
• Blood
• 2010

Dendritic cells (DCs) play an important role in viral infections both as initiators of immunity and as viral targets. Interaction between DCs and the innate-like CD1d-restricted natural killer T… (More)

Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector- to a memory-type response.

• K Blom, Monika Braun, +6 authors Johan K Sandberg
• Journal of immunology
• 2013

The live attenuated yellow fever virus (YFV) 17D vaccine provides a good model to study immune responses to an acute viral infection in humans. We studied the temporal dynamics, composition, and… (More)

Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection.

• Barbara L Shacklett, Catherine A. Cox, Johan K Sandberg, Neil H. Stollman, Mark A. Jacobson, Douglas F Nixon
• Journal of virology
• 2003

Gut-associated lymphoid tissue (GALT) is a significant but understudied lymphoid organ, harboring a majority of the body's total lymphocyte population. GALT is also an important portal of entry for… (More)

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