Johan H T Wagenvoort

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181 patients undergoing resection of the oesophagus for carcinoma were randomised to receive selective decontamination (test group) or conventional perioperative antibiotic prophylaxis (controls). 114 patients were finally included in the study: 12 of 56 test patients had 18 infections, whereas 32 of 58 controls acquired 51 infections. Colonisation with(More)
OBJECTIVE To test the hypothesis that perioperative elimination of nasal carriage of Staphylococcus aureus using mupirocin nasal ointment reduces the surgical-site infection (SSI) rate in cardiothoracic surgery. DESIGN Unblinded intervention trial with historical controls. SETTING A university hospital, tertiary referral center for cardiothoracic(More)
To evaluate the importance of nasal carriage of Staphylococcus aureus as a risk factor for the development of wound infection at the sternotomy site after cardiac surgery, a case-control study was done. The study population consisted of 1980 consecutive patients. Cases were all patients who developed a sternal wound infection from which S. aureus was(More)
Results from 8 Dutch hospitals participating in an international epidemiological surveillance project were analyzed to establish the prevalence of resistant Gram-negative species and to demonstrate the extent of cross-resistance. Overall resistance rates among the 828 isolates tested were lowest with imipenem, ciprofloxacin, amikacin, and tobramycin.(More)
To the Editor: In recent years, methicillinresistant Staphylococcus aureus (MRSA) of phage type III-29 has become the MRSA strain most frequently introduced to Dutch hospitals from other European countries.1 From July 1992 to July 1993, our 800bed regional teaching hospital experienced the continual presence of an MRSA III-29 strain that colonized or(More)
Environmental sources have been associated with prolonged epidemics of methicillin-resistant Staphylococcus aureus (MRSA). Our objective was to evaluate whether outbreak MRSA strains differ in their environmental survival from sporadic MRSA strains. The strains were detected in five adult patients unknowingly colonized by MRSA. The MRSA strains from(More)