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This article represents initial deliberation of an international task force appointed by the US National Multiple Sclerosis Society to develop recommendations for optimal clinical assessment tools for multiple sclerosis clinical trials. Presented within this article are the key issues identified by the task force during its initial year of deliberation.(More)
This article provides recommendations from the National Multiple Sclerosis Society's Clinical Outcomes Assessment Task Force. The Task Force was appointed in 1994 and charged with recommendending improved approaches for clinical outcomes assessment in future controlled clinical trials. The recommendations herein follow extensive deliberation and data(More)
We describe the background for and building of IcePaHC, a one million word parsed historical corpus of Icelandic which has just been finished. This corpus which is completely free and open contains fragments of 60 texts ranging from the late 12 th century to the present. We describe the text selection and text collecting process and discuss the quality of(More)
A pilot study was undertaken to test the safety and establish the side effect profile of recombinant human interferon-beta 1b (Betaseron, Berlex Laboratories, Richmond, CA), in patients with relapsing-remitting multiple sclerosis (RRMS). During the initial dose finding period (24 weeks), five groups of 6 patients each were treated by subcutaneous injection(More)
BACKGROUND Prognosis for the majority of children with brain stem gliomas is dismal. In previous studies, recombinant beta-interferon (r beta IF) has been shown to be effective for children with recurrent brain stem gliomas and may also act synergistically with radiotherapy (RT). METHODS Thirty-two children with diffuse intrinsic brain stem gliomas were(More)
We describe the background for and building of IcePaHC, a one million word parsed historical corpus of Icelandic which has just been finished. This corpus which is completely free and open contains fragments of 60 texts ranging from the late 12 th century to the present. We describe the text selection and text collecting process and discuss the quality of(More)
The Reflexive Passive in Icelandic is reminiscent of the so-called New Passive (or New Impersonal) in that the oblique case of a passivized object NP is preserved. As is shown by recent surveys, however, speakers who accept the Reflexive Passive do not necessarily accept the New Passive, whereas conversely, speakers who accept the New Passive do also accept(More)