Joel T. Katz

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OBJECTIVE Critically ill patients require high-intensity care and may be at especially high risk of iatrogenic injury because they are severely ill. We sought to study the incidence and nature of adverse events and serious errors in the critical care setting. DESIGN We conducted a prospective 1-year observational study. Incidents were collected with use(More)
The recent discovery of dideoxymycobactin (DDM) as a ligand for CD1a demonstrates how a nonribosomal lipopeptide antigen is presented to T cells. DDM contains an unusual acylation motif and a peptide sequence present only in mycobacteria, but its discovery raises the possibility that ribosomally produced viral or mammalian proteins that commonly undergo(More)
PURPOSE OF REVIEW Fungal infections of the central nervous system, once a relatively rare occurrence, are increasingly common due to the expansion of immunocompromised populations at risk, and therefore are important to recognize early and manage appropriately. RECENT FINDINGS The specific infectious risk posed by novel immune-modifying therapies can, in(More)
To those familiar only with Pablo Picasso's (1881–1973) groundbreaking modernism for which he is renown, his early realistic paintings may seem surprising. Born in the Mediterranean harbor of Málaga, " Pablito " (as Picasso was called by his family) was raised in tight quarters by an incorrigibly optimistic and good humored mother and an unoriginal painter(More)
Works by Francisco José de Goya y Lu-cientes (1746–1828) bridge the gulf in many ways, from the 18th-century Euro-pean masters to the early seeds of mod-ernism. In the wake of the revolution to the north and the Napoleonic Wars during his lifetime, tumultuous political and social upheavals in Spain impacted the artist, directly. Goya's artistic opus(More)
Although herpes simplex encephalitis is not classically considered an opportunistic infection, reactivation of herpes simplex is being seen increasingly in patients with cancer or immunosuppression. The authors present a patient with malignant glioma and HSV-1 encephalitis whose PCR-proven encephalitis recurred after temozolomide (TMZ) chemoradiation(More)
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