Joel E. Richardson

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Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the biological role of such shared proteins in one organism can often be transferred to other organisms. The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can(More)
The Mouse Genome Database, (MGD, http://www.informatics.jax.org/), integrates genetic, genomic and phenotypic information about the laboratory mouse, a primary animal model for studying human biology and disease. MGD data content includes comprehensive characterization of genes and their functions, standardized descriptions of mouse phenotypes, extensive(More)
The Mouse Genome Database (MGD) is the community model organism database for the laboratory mouse and the authoritative source for phenotype and functional annotations of mouse genes. MGD includes a complete catalog of mouse genes and genome features with integrated access to genetic, genomic and phenotypic information, all serving to further the use of the(More)
This paper presents an overview of EXODUS, an extensible database system project that is addressing data management problems posed by a variety of challenging new applications. The goal of the project is to facilitate the fast development of high-performance, application-specific database systems. EXODUS provides certain kernel facilities, including a(More)
The Mouse Genome Database (MGD) (http://www.informatics.jax.org) one component of a community database resource for the laboratory mouse, a key model organism for interpreting the human genome and for understanding human biology. MGD strives to provide an extensively integrated information resource with experimental details annotated from both literature(More)
provided by no commercial database system at this time). Storing This paper describes the design of the object-oriented storage component of EXODUS, an extensible database manaaement~svstern currently under development at the University of-Wiscon&t. The basic abstraction in the EXODU’S storage system is the storage object, an uninterpmted variable-length(More)
The type systems of most object-orientecl database syst ems ( 00 DBSS) descend from traditional object-oriented programming lan gna,ges. While these systems can capture many interesting relationships among entities, such as classification ancf snbtyping, they do not typically allow an object, to change type, and they only partially support the mode]ling of(More)
The Mouse Genome Database (MGD) forms the core of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a model organism database resource for the laboratory mouse. MGD provides essential integration of experimental knowledge for the mouse system with information annotated from both literature and online sources. MGD curates and(More)
The Mouse Genome Database (MGD, http://www.informatics.jax.org) is the international community resource for integrated genetic, genomic and biological data about the laboratory mouse. Data in MGD are obtained through loads from major data providers and experimental consortia, electronic submissions from laboratories and from the biomedical literature. MGD(More)
With non-traditional application areas such as engineering design, image/voice data management, scientific/statistical applications, and artificial intelligence systems all clamoring for ways to store and efficiently process larger and larger volumes of data, it is clear that traditional database technology has been pushed to its limits. It also seems clear(More)