Joeke Jurjen de Vries

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OBJECTIVE To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b treatment in patients with a first clinical event suggestive of multiple sclerosis (MS) (clinically isolated syndrome). METHODS We conducted a multicenter, randomized, double-blind, placebo-controlled trial. Patients with a first clinical demyelinating event and(More)
In ten growth retarded fetuses (IUGR) a qualitative and quantitative analysis was made of various movement patterns. The results were compared with those of ten matched appropriate-for-gestational age fetuses (AGA). The aim of the study was to see whether malnourished, growth retarded fetuses move differently to well nourished, normal fetuses. The real-time(More)
The differentiation between progressive supranuclear palsy (PSP) and Parkinson's disease (PD) may be difficult, especially in the early stages of disease. Positron emission tomography potentially provides a tool for making such a distinction. To identify key features in the spatial distributions of cerebral glucose metabolism, 18F-fluorodeoxyglucose (FDG)(More)
high-frequency ultrasound. Pre-operatively, we suspected that this most likely represented a benign smooth muscle tumor that had eroded through the iris root. Amyloid can occur as a localized ocular or widespread systemic process. Approximately 4% of amyloid deposits in the head and neck region involve the orbit. 7 Amyloid deposits in ophthalmic structures(More)
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