Joe McConnell

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In the mammalian retina, Thy-1, the most abundant mammalian neuronal surface glycoprotein, is found predominantly if not exclusively on retinal ganglion cells. We hypothesized that Thy-1 plays a significant role in retinal development. Neurite outgrowth of retinal ganglion cells from Thy-1(-) mice over multiple substrates was compared to that seen with(More)
The distribution of adrenergic and cholinergic nerves was studied in penile tissue from rat, rabbit, cat, monkey and man. Glyoxylic acid histofluorescence and acetylcholinesterase-positive fibers were found in all tissues examined, but histofluorescent, presumably adrenergic fibers predominated. In general, except in the rabbit, more nerve fibers of both(More)
The time of origin of the amygdaloid complex was studied in mice injected once with tritiated thymidine during gestation or early neonatal development. Neurons for this nucleus and related nuclei arose during embryonic days 11-15. No mediolateral or dorsoventral gradients, but a distinct rostrocaudal gradient of proliferation was evident in comparisons of(More)
The major organs of the male urogenital (UG) system have been examined in various mammals, including man, using light and electron microscopic (EM) histochemical methods. For the light microscopic study, the urinary bladder, the vas deferens and the penis (corpora cavernosa and corpus spongiosum) were studied in the rat, cat, dog, monkey and man using a(More)
Since a common problem in histochemical methods is the need for fresh-frozen tissue, techniques have been developed in this laboratory for the long-term storage and use of frozen tissue. Cryostat sections of tissue stored for as long as 4 years at -70 degrees C have been utilized to localize biogenic amines and acetylcholinesterase (AChE). The quality of(More)
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