Jochen Rieck

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Limbal epithelial stem cells (LESCs) are tissue-specific stem cells responsible for renewing the corneal epithelium. Acute trauma or chronic disease affecting LESCs may disrupt corneal epithelial renewal, causing vision threatening and painful ocular surface disorders, collectively referred to as LESC deficiency (LESCD). These disorders cannot be treated(More)
Deletions and translocations of human chromosome region 3p14 are considered to be involved in the development of various human malignancies, suggesting the existence of at least one tumor suppressor gene in human chromosome region 3p14. To analyze this region we constructed a YAC-contig from the distal region of 3p13 to the proximal part of 3p21. The contig(More)
Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) provide an unlimited cell source for retinal cell replacement therapies. Clinical trials using hESC-RPE to treat diseases such as age-related macular degeneration (AMD) are currently underway. Human ESC-RPE cells have been thoroughly characterized at the gene level but their(More)
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