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In this review, we hypothesized the importance of the interaction between the brain glutathione (GSH) system, the proteolytic tissue plasminogen activator (t-PA)/plasminogen/ plasmin system,… (More)
Sulodexide is a highly purified glycosaminoglycan containing a combination of heparan sulfate with affinity for antithrombin III and dermatan sulfate with affinity for heparin cofactor II. This… (More)
Stress, inflammation and Plasminogen activator inhibitor 1 (PAI-1) are key mechanisms throughout the development of aging, constituting a crossroad in the most frequent pathologies that accompany it.… (More)
Cancer is a group of diseases that are characterized by the development of abnormal cells, which divide almost without limit, develop, spread without control anywhere in the body, losing the cells… (More)
Decades ago Hans Hugo Bruno Selye expressed the concept of stress as a pathophysiological syndrome generated by various endogenous / exogenous harmful agents and named it as the "General Adaptation… (More)