Joaquín Fernández-Crehuet Navajas

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To investigate the relationship between trans fatty acids and postmenopausal breast cancer in European populations differing greatly in their dietary fat intakes, a case control study using adipose tissue stores of trans fatty acids as a biomarker of exposure was conducted. Subjects included 698 postmenopausal incident cases of primary breast cancer and(More)
The strongest evidence that monunsaturated fat may influence breast cancer risk comes from studies of southern European populations, in whom intake of oleic acid sources, particularly olive oil, appears protective. No previous study has examined the relation of adipose tissue fatty acid content to breast cancer in such a population. We used adipose biopsies(More)
The aim of the present study was to assess the cost-benefit of the program of fluoridation of the public water supply in the city of Málaga. Marginal benefits and the rate cost/benefit were the two parameters used to evaluate the cost-benefit. We have considered all the information available about similar experiences performed in other countries and about(More)
OBJECTIVE To study relationships between habitual dietary intake, adipose tissue concentrations of alpha-carotene, beta-carotene and lycopene, and plasma concentrations of alpha- and beta-carotene. DESIGN Cross-sectional study including assessment of food habits by a food frequency questionnaire and 48-hour recall and determination of carotenoid(More)
Iron is the second most abundant metal in the Earth's crust. Despite being present in trace amounts, it is an essential trace element for the human body, although it can also be toxic due to oxidative stress generation by the Fenton reaction, causing organic biomolecule oxidation. This process is the basis of numerous pathologies, including cardiovascular(More)
INTRODUCTION The high prevalence of disease-related hospital malnutrition justifies the need for screening tools and early detection in patients at risk for malnutrition, followed by an assessment targeted towards diagnosis and treatment. At the same time there is clear undercoding of malnutrition diagnoses and the procedures to correct it Objectives: To(More)
OBJECTIVE To describe the psychosocial environment of health professionals in public health in primary and hospital care, and compare it with that of the general Spanish working population, as well as to evaluate the effect of psychosocial risk factors on symptoms related to perceived stress. DESIGN Cross-sectional study with stratified random sampling.(More)