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The minimization of the capital expenditures associated to supporting services with different bandwidth requirements in an Optical Transport Network (OTN) demands accounting for transceiver cost and transmission performance when dimensioning the network. Developments in 40 Gb/s and 100 Gb/s transceiver technology will condition the relative cost and maximum(More)
OBJECTIVE Considering the relevance of tumor necrosis factor-alpha (TNF-alpha) in the pathophysiology of juvenile idiopathic arthritis (JIA), it is likely that polymorphisms in its promoter area may be relevant in disease susceptibility and activity. We investigated if clinical measures of JIA activity and TNF-alpha serum concentrations were associated with(More)
AIM To examine correlates of unhealthy weight-control behaviours (UNWCB), and to explore possible associated variables. METHODS Sample included 3762, 8th and 10th grade public school Portuguese students who participated in the 2002 Health Behaviour in School-Aged Children (HBSC)/World Health Organization (WHO) survey of adolescent health. Factor analysis(More)
OBJECTIVE To identify psychosocial and lifestyle indicators including alcohol consumption, that may distinguish overweight and obese adolescents from their peers, and align them with other adolescents with chronic conditions. METHODS The sample included 6 131 6th, 8th, and 10th grade public school Portuguese students, aged 11-16 years, who participated in(More)
To assess the interaction among androgens, placenta, and the hypothalamo-pituitary-adrenal axis we studied effects of androstenedione administered intravascularly to the pregnant monkey on maternal plasma CRH, ACTH, dehydroepiandrosterone sulfate (DHEAS), cortisol, and estradiol concentrations. Ten monkeys (128 +/- 3 days gestation; mean +/- SEM) were(More)
This paper aims to review the status of standardization activities on the black link (BL) and corresponding alien wavelength concepts. It discusses experimental work on filterless optical networks conducted within a dedicated Deutsche Telekom project. The general prospects and existing challenges concerning elastic extensions of the BL are also assessed.(More)
The growing relevance of wireless communications has been driving the research and development of advanced network architectures to enable the cost-effective support of large numbers of users at very high data rates. In this context, the FUTON project aims to fulfil the objectives of the so-called 4th Generation (4G) through an innovative Distributed(More)
Flex-rate transmission is seen as a core element in the realization of programmable backbone networks. The ability to adjust the channel bit rate in response to traffic changes in the network can potentially bring long-term savings by future-proofing capacity and simplifying network operations. The key issue in this topic is quantifying the degree of(More)
Fast developments in the transport network ecosystem are putting into question the foundations on which to base next-generation backbone networks. Flexibility is touted as an essential requirement to cope with traffic increasing in volume and unpredictability. Based on this principle, flexible transmission modules such as the sliceable bandwidth-variable(More)
The sliceable bandwidth-variable transponder (SBVT) has been recently proposed as a transmission module able to combine the scalability of superchannel-based transmission with the flexibility required for highly meshed traffic. The modular nature of the SBVT implies that a large array of transmission capacity is predeployed per module, which significantly(More)