Joao ML Dias

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
BACKGROUND Novel analytical tools, which shorten the long and costly development cycles of biopharmaceuticals are essential. Metabolic flux analysis (MFA) shows great promise in improving our understanding of the metabolism of cell factories in bioreactors, but currently only provides information post-process using conventional off-line methods. MFA(More)
The use of CBM (Condition Based Maintenance) on critical equipment allows on-line monitoring of equipment vibration level, for instance. The analysis of unstructured data generated by vibration sensors can cause false alarms, in particular when several variables are analyzed. Therefore, T<sup>2</sup> multivariate statistical control charts can play an(More)
  • 1