Joanne Curry O'Connell

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The PDE4A (type IV) cAMP-specific, rolipram-inhibited phosphodiesterase RPDE-6 (RNPDE4A5), when transiently expressed in COS7 cells, could be complexed with the v-Src-SH3 domain expressed as a glutathione S-transferase (GST) fusion protein. RPDE-6 did not interact with GST itself. This complex was not disrupted by treatment with high NaCl concentration(More)
Of the five PDE4D isoenzymes, only the PDE4D4 cAMP specific phosphodiesterase was able to bind to SH3 domains. Only PDE4D4 and PDE4A5, but not any other PDE4A, B, C and D isoforms expressed in rat brain, bound to src, lyn and fyn kinase SH3 domains. Purified PDE4D4 could bind to purified lyn SH3. PDE4D4 and PDE4A5 both exhibited selectivity for binding the(More)
Family issues are the main focus of this document, one in a series of seven bibliographies dealing with rehabilitation of disabled Native Americans. The 23 annotated entries were identified through a comprehensive search of relevant data bases covering the years 1966-1986 and were selected to be of use to consumers, policy makers, direct service providers,(More)
The Native American population remains a special ethnic group in the United States that is overrepresented at the lower end of the socioeconomic scale, with a suspected greater than average rate of disabling conditions. Utilization of rehabilitation services by adult Native Americans was studied. Three years of Rehabilitation Services Administration (RSA)(More)
This annotated bibliography is part of a series that offers a synthesis of knowledge on rehabilitation of Native Americans who are disabled. This volume of the series covers mental health issues and lists, alphabetically by author, a total of 65 books, dissertations, journal articles, and reports issued between 1967 and 1985. (JDD)(More)