Joanna Jakubowska

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VisGenome visualizes single and comparative representations for the rat, the mouse and the human chromosomes at different levels of detail. The tool offers smooth zooming and panning which is more flexible than seen in other browsers. It presents information available in Ensembl for single chromosomes, as well as homologies (orthologue predictions including(More)
Degraded DNA is often analyzed in forensic genetics laboratories. Reliable analysis of degraded DNA is of great importance, since its results impact the quality and reliability of expert testimonies. Recently, a number of whole genome amplification (WGA) methods have been proposed as preamplification tools. They work on the premise of being able to generate(More)
We present a novel approach to XML data integration which allows a biologist to select data from a large XML file repository, add it to a genome map, and produce a mapping mashup showing integrated data in map context. This approach can be used to produce contextual views of arbitrary XML data which relates to objects shown on a map. A biologist using(More)
We synthesised seven 2-aminestilbenes with methoxy substitents in reactions of dinitrostilbenes with sodium azide. In order to study the positioning of the nitro groups, the optimum structure of obtained stilbenes using the DFT B3LYP/6-311++G(2d,p) method was calculated. Very interesting aspect of this regioselectivity reaction is the fact that in all(More)
Brown tumors are rare skeletal manifestations of hyperparathyroidism (HPT) that may mimic cancer metastases. Histopathologically, they are difficult to differentiate from other giant cell lesions. A case is presented of 41-year-old woman with giant cell tumor in parieto-occipital region with injury of external bone lamina, growing into the skull cavity. The(More)
There is a necessity for deceased identification as a result of many accidents and sometimes bones are the only accessible source of DNA. So far, a universal method that allows for extraction of DNA from materials at different stages of degradation does not exist. The aims of this study were: the comparison of three methods of DNA extraction from bones with(More)
It is not always clear how best to represent integrated data sets, and which application and database features allow a scientist to take best advantage of data coming from various information sources. To improve the use of integrated data visualisation in candidate gene finding, we carried out a user study comparing an existing general-purpose genetics(More)
We focus on visualisation techniques used in genome browsers and report on a new technique, CartoonPlus, which improves the visual representation of data. We describe our use of smooth zooming and panning , and a new scaling algorithm and focus on options. CartoonPlus allows the users to see data not in original size but scaled, depending on the data type(More)
In order to address the needs of data visualization software we propose that e-Science should support the dynamic load balancing of data integration agents and that this mechanism could be supported by grids of collaborating computing infrastructures. Examples will be given of a service tailored along these lines to support visualization client software.(More)