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  • David Cunningham, Eliza A Hawkes, +13 authors David C. Linch
  • Medicine
  • The Lancet
  • 1 May 2013
  • BACKGROUND Dose intensification with a combination of cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) every 2 weeks improves outcomes in patients older than 60 years with diffuseContinue Reading
  • Mary Kay Gleeson, Nicholas Counsell, +16 authors David C. Linch
  • Medicine
  • Annals of oncology : official journal of the…
  • 1 October 2017
  • Background Central nervous system (CNS) relapse of diffuse large B-cell lymphoma (DLBCL) is associated with a dismal prognosis. Here, we report an analysis of CNS relapse for patients treated withinContinue Reading
  • Andrea Kühnl, David Cunningham, +22 authors David C. Linch
  • Medicine
  • Annals of oncology : official journal of the…
  • 1 July 2017
  • Background There is an on-going debate whether 2- or 3-weekly administration of R-CHOP is the preferred first-line treatment for elderly patients with diffuse large B-cell lymphoma (DLBCL). The UKContinue Reading
  • Mary Kay Gleeson, Eliza A Hawkes, +16 authors David C. Linch
  • Medicine
  • British journal of haematology
  • 1 November 2016
  • We performed a subgroup analysis of the phase III UK National Cancer Research Institute R-CHOP-14 versus R-CHOP-21 (two- versus three-weekly rituximab, cyclophosphamide, doxorubicin, vincristine andContinue Reading
  • Simon Rule, Paul W. Smith, +4 authors David C. Linch
  • Medicine
  • Journal of clinical oncology : official journal…
  • 20 May 2009
  • 8555 Background: Mantle cell lymphoma (MCL) remains an incurable malignancy with conventional chemotherapeutic options with little randomised evidence to help direct therapy. The InternationalContinue Reading