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Lack of a Fusion Requirement for Development of Bone Marrow-Derived Epithelia
Analysis of developmental plasticity of bone marrow–derived cells (BMDCs) is complicated by the possibility of cell-cell fusion. Here we demonstrate that epithelial cells can develop from BMDCsExpand
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Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow.
OBJECTIVE To better understand the process by which pneumocytes can be derived from bone marrow cells, we investigated the in vivo kinetics of such engraftment following lethal irradiation. METHODSExpand
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Bone marrow-derived cells contribute to epithelial engraftment during wound healing.
Recent findings suggest that bone marrow-derived cells (BMDC) may contribute to tissue maintenance throughout the body. However, it is not yet known whether marrow-derived epithelial cells areExpand
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Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium.
Gene therapy application to pulmonary airways and alveolar spaces holds tremendous promise for the treatment of lung diseases. However, safe and effective long-term gene expression using viral andExpand
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Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice.
OBJECTIVE For approximately 5% of autologous transplant recipients and a higher proportion of allogeneic transplant recipients, low level and delayed platelet engraftment is an ongoing problem.Expand
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Plasticity of bone marrow-derived stem cells.
Stem cell plasticity refers to the ability of adult stem cells to acquire mature phenotypes that are different from their tissue of origin. Adult bone marrow cells (BMCs) include two populations ofExpand
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Cell Injury , Repair , Aging and Apoptosis Bone Marrow-Derived Cells Contribute to Epithelial Engraftment during Wound Healing
Recent findings suggest that bone marrow-derived cells (BMDC) may contribute to tissue maintenance throughout the body. However, it is not yet known whether marrow-derived epithelial cells areExpand
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Engraftment of bone marrow-derived epithelial cells
The long-held concept that transplanted bone marrow (BM)-derived cells contribute only to cells of the hematopoietic system was challenged by data from our laboratory showing that a single maleExpand
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Aging and Apoptosis Bone Marrow-Derived Cells Contribute to Epithelial Engraftment during Wound Healing
Recent findings suggest that bone marrow-derived cells (BMDC) may contribute to tissue maintenance throughout the body. However, it is not yet known whether marrow-derived epithelial cells areExpand