Joana Patrícia dos Santos Carvalho

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In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influencing various physiological and pathological functions of both recipient and parent cells. While intensive(More)
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffuse gastric cancer (HDGC). Reliable estimates of cancer risk and spectrum in germline mutation carriers are essential for management. For families without CDH1 mutations, genetic-based risk stratification has not been possible,(More)
OBJECTIVE The aims of this study were (1) to assess the relationships between transport to and from school (active vs. passive), sedentary behaviours, measures of socio-economic position and perceived environmental variables, and (2) to determine which, if any, variables were predictors of active transportation. METHODS The sample comprised 705 girls with(More)
Patterns of substitution in chloroplast encoded trnL_F regions were compared between species of Actaea (Ranunculales), Digitalis (Scrophulariales), Drosera (Caryophyllales), Panicoideae (Poales), the small chromosome species clade of Pelargonium (Geraniales), each representing a different order of flowering plants, and Huperzia (Lycopodiales). In total, the(More)
The prevalence of immune-related systemic manifestations associated with inflammatory bowel disease varies widely in different studies. This prospective hospital study examines the prevalence and clinical aspects of these manifestations. A total of 792 patients, 449 with Crohn's disease and 343 with ulcerative colitis, were followed up from diagnosis to 20(More)
This article documents the performance of the ATLAS muon identification and reconstruction using the LHC dataset recorded at √ s = 13 TeV in 2015. Using a large sample of J/ψ → μμ and Z → μμ decays from 3.2 fb −1 of pp collision data, measurements of the reconstruction efficiency , as well as of the momentum scale and resolution, are presented and compared(More)
A search is presented for direct top squark pair production in final states with one isolated electron or muon, jets, and missing transverse momentum in proton-proton collisions at sqrt[s] = 7 TeV. The measurement is based on 4.7 fb(-1) of data collected with the ATLAS detector at the LHC. Each top squark is assumed to decay to a top quark and the lightest(More)
A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual(More)
OBJECTIVE The purpose of this study was to assess the associations and impact of increased meal frequency, physical activity and 'skipping' breakfast on obesity levels in a sample of urban adolescents, aged 13-17 years old, from Porto, Portugal. METHODS Overweight and obesity were defined according to age- and sex-specific BMI cut-points. Daily meal(More)
Previous studies investigated the associations between health-related quality of life (HRQoL) and self-reported physical activity (PA) and/or self-reported physical fitness which are not the most reliable methods to assess PA and fitness. Therefore, this study aimed to examine the associations between HRQoL and each of objectively assessed habitual PA and(More)