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Activation of the opioid receptor results in short-term inhibition of intracellular cAMP levels followed by receptor desensitization and subsequent increase of cAMP above the control level (adenylyl cyclase superactivation). Using adenovirus to deliver pertussis toxin-insensitive mutants of the alpha-subunits of G(i/o) that are expressed in neuroblastoma(More)
The symbols in the table of contents identify articles discussed in the Perspective. Molecular Pharmacology (ISSN 0026-895X) is published monthly (two volumes per year beginning in January and July) by the Amer
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