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BACKGROUND Oxidative stress plays a role in acute and chronic inflammatory disease and antioxidant supplementation has demonstrated beneficial effects in the treatment of these conditions. This study was designed to determine the optimal dose of an antioxidant supplement in healthy volunteers to inform a Phase 3 clinical trial. METHODS The study was(More)
BACKGROUND Isolated fucoidans from brown marine algae have been shown to have a range of anti-inflammatory effects. PURPOSE This present study tested a Maritech((R)) extract formulation, containing a blend of extracts from three different species of brown algae, plus nutrients in an open label combined phase I and II pilot scale study to determine both(More)
BACKGROUND Isolated fucoidans from brown marine algae have been shown to have a range of immune-modulating effects. This exploratory study aimed to determine whether a seaweed nutrient complex containing a blend of extracts from three different species of brown algae plus nutrients is safe to administer and has biological potential as an immune modulator.(More)
The algesic properties of nocitoxin--a single monomeric, soluble protein responsible for significant algesia--were assessed through human bioassay to gauge nocitoxin's potential for use as a clinical pain stimulus. The hypothesis guiding this study stated that subjects tested with crude bullrout venom or nocitoxin will report experience of pain consistent(More)
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