Joan K Fisher

Learn More
There are many disease processes, both inflammatory and neoplastic, which can alter the colonic bowel wall. A retrospective study was done on surgically proven cases of colonic disease in which colonic bowel wall abnormalities were identified by computed tomography. Colonic bowel wall thickening was the most common finding, but was nonspecific. Finger-like(More)
We report two unusual cases of giant sigmoid diverticulum, which is a rare manifestation of diverticular disease. Giant diverticula are 3 to 4 cm or greater in size and are produced by gradual enlargement of an acquired pseudodiverticulum that has had superimposed infection, abscess formation, and healing. For more than 3 years, we have observed and managed(More)
We studied changes in cardiovascular and pulmonary function during prolonged endotoxemia in conscious sheep. Sheep with chronic lung lymph fistulas received a 12-h infusion of Escherichia coli endotoxin (10 ng x kg-1 x min-1) and allowed to recover for 12 h. Supportive therapies were withheld. Prolonged endotoxemia without volume support caused systemic(More)
A case of distal ileal diverticulosis complicated by diverticulitis causing partial small bowel obstruction is presented. To the author's knowledge, this is the first reported case of such obstruction, and the third reported case of preoperatively diagnosed ileal diverticulitis. This diagnosis should be considered in patients with acute abdominal symptoms(More)
OBJECTIVE We designed a prospective study to determine the frequency of retroperitoneal air after endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy. We sought to elucidate the relationship of retroperitoneal air with endoscopic maneuvers, clinical findings, the length of sphincterotomy, and the time spent during the procedure. We(More)
Plasma levels of tumor necrosis factor-alpha (TNF-alpha) peak between 2 and 4 h during a 12-h continuous infusion of endotoxin in awake sheep. We hypothesized that a source of this TNF-alpha is the pool of leukocytes that accumulate in the pulmonary circulation. To test this hypothesis, we physiologically monitored six anesthetized sheep during baseline and(More)