Joachim Krauth

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The assumptions upon which a correct interpretation of the t-test depends are rarely fulfilled by data from the neurosciences. This applies to both independent and correlated samples. The Mann-Whitney U-test is suggested as an alternative for the t-test for independent samples. The way in which significant results from this test should be interpreted is(More)
The tuberomammillary nucleus (TM), located in the posterior hypothalamic region, consists of five subgroups and is the only known source of brain histamine. In the present experiment, rats received bilateral ibotenic acid or sham lesions in the rostroventral part of the TM (E2-region). Three weeks later they were tested on the elevated plus-maze test of(More)
Whereas convincing evidence exists for an important role of the hippocampus in mechanisms underlying memory and encoding of location in space, the contribution of the hippocampus to the system underlying central processes of reinforcement is less well established. Scattered data suggesting that hippocampal ablation increases the effectiveness of positive(More)
The purpose of this experiment was to investigate whether the neurokinin substance P (SP) can enhance adaptive graft effects on learning and memory functions in animals with lesions of the hippocampus. Adult male Wistar rats received a bilateral kainic acid (KA) lesion of the dorsal hippocampus. One week postlesion, bilateral grafts of fetal hippocampal(More)
In conditioned place preference experiments, groups of animals are typically compared by means of the total time spent in a treatment environment. The total times are often positively skewed, which prohibits the use of parametric procedures that require normal distributions. Common response time models for such total times are also inadequate because the(More)
The extended-return-map was employed to analyze the inter-response time data of operant experiments using fixed-interval schedules and food reinforcement. After intensive training over numerous sessions, rats gradually developed several types of temporal patterns of lever pressing behaviors, which were visualized through different patterns of data point(More)
Freedman (1990) introduced a computer analog of the shuttlebox paradigm and presented results to show that this analog could be used for studying human avoidance conditioning. In the present study, a first experimental phase was conducted to test how the fact that the tone was considered aversive in the instructions and the intensity of this tone affect(More)