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Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β

• Jiangming Luo, Róbert Sládek, Jo-Ann Bader, Annie Matthyssen, Janet Rossant, Vincent Giguère
• Nature
• 1997

Classical endocrine studies have shown that steroid hormones are required for the maintenance of pregnancy and placental viability. The oestrogen-receptor-related receptor β (ERR-β) is an orphan… (More)

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha.

• Jiangming Luo, Róbert Sládek, Julie Carrier, Jo-Ann Bader, Denis Richard, Vincent Giguère
• Molecular and cellular biology
• 2003

The estrogen-related receptor alpha (ERRalpha) is an orphan member of the superfamily of nuclear hormone receptors expressed in tissues that preferentially metabolize fatty acids. Despite the… (More)

Orphan nuclear receptor RORα-deficient mice display the cerebellar defects of staggerer

• Isabelle Dussault, Diana Fawcett, Annie Matthyssen, Jo-Ann Bader, Vincent Giguère
• Mechanisms of Development
• 1998

It has recently been shown that the neurological mutant mouse staggerer (sg) harbors a deletion within the Rora gene that encodes the orphan nuclear receptor ROR alpha. This deletion removes an exon… (More)

Compound mutants for retinoic acid receptor (RAR)β and RARα1 reveal developmental functions for multiple RARβ isoforms

• Jiangming Luo, Henry M Sucov, Jo-Ann Bader, Ronald M Evans, Vincent Giguère
• Mechanisms of Development
• 1996

Mice with targeted disruptions in retinoic acid receptor genes have been generated to assess the role of nuclear receptors as transducers of the retinoid signal during vertebrate development. Mice… (More)