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- Publications
- Influence
Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β
- J. Luo, R. Sládek, Jo-Ann Bader, Annie Matthyssen, J. Rossant, V. Giguère
- Biology, Medicine
- Nature
- 21 August 1997
Classical endocrine studies have shown that steroid hormones are required for the maintenance of pregnancy and placental viability. The oestrogen-receptor-related receptor β (ERR-β) is an orphan… Expand
Reduced Fat Mass in Mice Lacking Orphan Nuclear Receptor Estrogen-Related Receptor α
- J. Luo, R. Sládek, J. Carrier, Jo-Ann Bader, D. Richard, V. Giguère
- Biology, Medicine
- Molecular and Cellular Biology
- 15 November 2003
ABSTRACT The estrogen-related receptor α (ERRα) is an orphan member of the superfamily of nuclear hormone receptors expressed in tissues that preferentially metabolize fatty acids. Despite the… Expand
Orphan nuclear receptor RORα-deficient mice display the cerebellar defects of staggerer
- I. Dussault, D. Fawcett, Annie Matthyssen, Jo-Ann Bader, V. Giguère
- Biology, Medicine
- Mechanisms of Development
- 1998
It has recently been shown that the neurological mutant mouse staggerer (sg) harbors a deletion within the Rora gene that encodes the orphan nuclear receptor ROR alpha. This deletion removes an exon… Expand
Compound mutants for retinoic acid receptor (RAR)β and RARα1 reveal developmental functions for multiple RARβ isoforms
- J. Luo, H. Sucov, Jo-Ann Bader, R. Evans, V. Giguère
- Biology
- Mechanisms of Development
- 1 March 1996
Mice with targeted disruptions in retinoic acid receptor genes have been generated to assess the role of nuclear receptors as transducers of the retinoid signal during vertebrate development. Mice… Expand