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Turmeric, obtained from the rhizomes of Curcuma longa, is used in South Asia as a traditional medicine for the treatment of epilepsy. To date, in vivo studies on the anticonvulsant activity of turmeric have focused on its principal curcuminoid, curcumin. However, poor absorption and rapid metabolism have limited the therapeutic application of curcumin in(More)
The title compound, [Pd(C(12)H(10)ClN(2)O(2))Cl(C(18)H(15)P)(2)], is the inter-mediate of the reduction of a 3,5-dichloro-pyrazinone [Loosen, Tutonda, Khorasani, Compernolle & Hoornaert (1991 ▶). Tetra-hedron, 47, 9259-9268]. This species is formed by oxidative addition of coordinatively unsaturated Pd(0) to the reactive 3-position of the heterocycle. The(More)
In the title compound, C(11)H(9)BrN(2)O, the mol-ecules are linked into R(2) (2)(8) dimers by paired N-H⋯O hydrogen bonds and these dimers are further stacked into columns along the c axis by π-π inter-actions between pyrazinone rings [centroid-centroid distance = 3.544 Å; the dihedral angle between the planes of these rings is 7.51 (16)°]. The title(More)
In the crystal structure of the title compound, C(26)H(24)N(2)O(2), weak inter-molecular C-H⋯π inter-actions involving the benzene of the p-methoxy benzyl group and one of the phenyl rings result in the formation of chains consisting of alternating enanti-omers. Weak C-H ⋯O inter-actions with the methoxy O atom lead to the formation of layers, which are(More)
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