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Tau hyperphosphorylation, amyloid plaques, and neuronal death are major neuropathological features of Alzheimer’s disease (AD) and Prion-related encephalopathies (PRE). Cyclin-dependent kinase 5(More)
Amyloid-β peptides (Aβ), the proposed triggers of synaptic dysfunction in early Alzheimer’s disease (AD), derive from the endoproteolytic cleavage of amyloid-β precursor protein (APP) by β-secretases(More)