João Madaleno

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BACKGROUND Implementation of surveillance programs for at-risk populations and identification of biomarkers for early hepatocellular carcinoma (HCC) detection are a major public health goal. Recently, osteopontin (OPN) has attracted attention as a promising biomarker, with some potential advantages compared to alpha-fetoprotein (AFP), but its role in the(More)
BACKGROUND Subcortical hypodensities of presumed vascular etiology (SHPVO) are a clinical, radiological and neuropathological syndrome with a still largely unexplained pathophysiology. Parallel to the clinical heterogeneity, there is also recognised cerebral topographical diversity with undetermined etiological implications. Our aim is to assess clinical(More)
The presence of hydrogen in as-grown carbon nanotubes (CNTs) synthesized by microwave plasma (MP) chemical vapour deposition (CVD) technique is demonstrated. Our results showed that the MPCVD, as-grown CNTs were hydrogenated consisting of C-H bonds; whereas, the tubes synthesized by arc discharge consisted of non-hydrogenated multi-walled CNTs. Fourier(More)
uberculosis (TB) remains a major global health problem, esponsible for the ill health of millions of people each year, nd ranks as the second leading cause of death from an nfectious disease worldwide.1 A variety of clinical manifesations are associated directly or indirectly with TB. Among hem, hematological abnormalities can be found in both he pulmonary(More)
The Hot Filament Chemical Vapour Deposition (HFCVD) method was employed to study hydrogen adsorption on multi-walled carbon nanotubes (MWCNTs) modified by nickel doping. Prior to the nickel doping, effective functionalisation of CNTs was achieved by treating them in HNO3/H2O2 medium. Samples were characterized using Scanning Electron Microscopy (SEM),(More)
BACKGROUND Incidental hepatocellular carcinomas (iHCCs) are tumors discovered on the explanted liver that were not present on imaging before transplantation. The natural history, histopathologic characteristics, and prognosis are not clearly defined. METHODS We compared the characteristics of iHCC and previously known hepatocellular carcinoma (pkHCC) in(More)
Background: Transcranial Doppler Pulsatility Index (PI) has traditionally been interpreted as a descriptor of distal cerebrovascular resistance. Many authors have investigated its usefulness in the context of traumatic brain injury (TBI), subarachnoid hemorrhage (SAH) and hydrocephalus. Nonetheless, many doubts remain about its interpretation in(More)
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