João José Vasco Furtado

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The Brazilian legislation did not recognize pharmaceutical patents for products and processes up until 1996, an exemption which started in 1945 for products and 1969, for processes. In this period, the domestic companies freely reproduced medicines developed by large companies from abroad and commercialized them in the local market with their own(More)
Universal design of user interfaces attempts to cover design issues in multiple contexts of use where multiple types of users may carry out multiple tasks, possibly on multiple domains of interest. Existing design methods do not necessarily support designing such user interfaces. A new design method is presented for this purpose in three layers: (i) a(More)
Universal design of user interfaces addresses design issues in multiple contexts of use where multiple types of users carry out multiple tasks, possibly in multiple domains of interest. Existing development methods do not necessarily support the development of such user interfaces, as they do not establish commonalities and differences between these(More)
Systemic lupus erythematosus (SLE) is an autoimmune disorder with a worldwide distribution, potentially life-threatening with considerable morbidity. The elimination of pathogenic B cells has emerged as a rational therapeutic option. Many open label studies have reported encouraging results in which clinical and serological remission have invariably been(More)
The probabilistic concept formation general problem in dealing with mixed-data scale environments is due to the use of different evaluation function for each attribute type. We claim that different behaviors for discrete and continuous evaluation functions are due to an unbalanced contribution for each attribute-type evaluation function inside the main(More)
In this article we describe a multi-agent system integrated into a Knowledge Management Information System, called MC2, for knowledge discovery in database. MC2 brings together a set of tools that contribute to the knowledge management process by allowing for the creation and maintenance of an organizational memory. To achieve this end, the approach taken(More)
Thi s article examines some theoretical approaches in support of industrial policy in Brazil, with special emphasis on the neo-Schumpeterian/evolutionary approach. This approach is applied to the analysis of some satisfactory experiences in the field of industrial policy and economic development in Brazil up to the end of the 1970s, and some unsuccessful(More)
During the course of a differential screen to identify transcripts specific for chick heart/hemangioblast precursor cells, we have identified Ccbe1 (Collagen and calcium-binding EGF-like domain 1). While the importance of Ccbe1 for the development of the lymphatic system is now well demonstrated, its role in cardiac formation remained unknown. Here we show(More)
More frequently, design of user interfaces covers design issues related to multiple contexts of use where multiple stereotypes of users may carry out multiple tasks, possibly on multiple domains of interest. Existing development methods do not necessarily support developing such user interfaces as they do not factor out common parts between similar cases(More)