João França Lopes

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The evaluation of the appearance of the optic disk is central to the diagnosis and management of patients with glaucoma. Grouping patients into categories, monitoring change, and quantitating the rate of change all require some type of quantitative staging of the amount of damage. Though the scientific literature regarding the appearance of the optic disk(More)
PURPOSE To investigate the efficacy of subconjunctival sodium hyaluronate 2.3% in increasing the success rate of glaucoma filtering surgery and promoting filtering blebs with characteristics presumed to predict better success. DESIGN Randomized controlled clinical trial. PARTICIPANTS Fifty-five patients scheduled for glaucoma surgery. INTERVENTION(More)
AIM To determine the effect of personality on vision-specific health-related quality of life (HRQoL). METHODS Based on power calculations, 148 individuals diagnosed as having glaucoma or ocular hypertension, without ocular comorbidity, were selected using criteria that included age over 30, no recent or upcoming surgery, the absence of a diagnosis of(More)
PURPOSE To determine if postoperative topical cyclosporine 0.05% has any beneficial effect following trabeculectomy. METHODS This was an interventional, randomized, prospective, double-masked clinical trial of 44 consecutive patients with uncontrolled glaucoma requiring filtration surgery. Ocular surface disease index questionnaire and comprehensive(More)
OBJECTIVE To assess ocular discomfort upon instillation and patient preference for brinzolamide/timolol relative to dorzolamide/timolol, in patients with open-angle glaucoma or ocular hypertension. METHODS This was a multicenter, prospective, patient-masked, randomized, crossover study. On day 0, patients received one drop of brinzolamide/timolol in one(More)
BACKGROUND Prostaglandin analogs reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension; however, these medications may affect the ocular surface and elicit ocular discomfort when preserved with benzalkonium chloride (BAK). METHODS This was an open-label, single-arm study conducted in Latin America from February 2012(More)
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